.jpeg.jpg "Aman Singh, MSc PhD photo")
PhD Candidate
Western University, Canada
Aman Singh, MSc
PhD Candidate, Department of Medical Biophysics
Schulich School of Medicine & Dentistry, Western University
Aman Singh is a PhD candidate in the Department of Medical Biophysics at Western University, Canada, where he investigates novel mechanisms of endothelial dysfunction in cardiovascular disease. Under the supervision of Dr. Krishna Singh, his research examines the role of BRCA2 in regulating endothelial responses to stressors such as Angiotensin II, TNF-α, and high glucose. His work integrates in vitro studies with human endothelial cell models and in vivo mouse models, employing approaches such as Digital Spatial Profiling to analyze endothelial-specific transcriptomic changes.
Aman utilizes a broad range of molecular and cellular techniques, including qPCR, Western blotting, RNA/protein extraction, immunofluorescence, and functional assays. He holds an MSc in Chemistry from Guru Nanak Dev University and postgraduate diplomas in Cannabis Applied Science and Research & Evaluation from Fanshawe College, reflecting a multidisciplinary background bridging molecular biology, cardiovascular , and translational research.
He has co-authored several peer-reviewed publications in journals such as International Journal of Molecular Sciences, Biomolecules, Journal of Biological Chemistry, and Journal of Molecular and Cellular Cardiology Plus. His recent work has advanced understanding of the interplay between DNA damage, autophagy, and endothelial-to-mesenchymal transition (EndMT).
Aman’s contributions have been recognized with the Best Poster Presentation Award at London Health Research Day 2025. He has presented at national and international conferences, mentors undergraduate students, serves as a Teaching Assistant, and contributes to the Academic Mentorship Program and International Commission of the Society of Graduate Students at Western.
With expertise in in vivo and in vitro endothelial biology, molecular profiling, scientific writing, and experimental design, Aman is committed to advancing BReast Cancer, vascular biology research and plans to pursue a postdoctoral fellowship focused on endothelial dysfunction and cancer biology.